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Mosquito Bites Leave A Lasting Impression On Our Immune System

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Mosquito bites are like a gross form of French kissing — the insects swap your blood with their saliva, and leave a trail of salivary secretions behind like mosquito cooties. Some of those compounds prevent clotting as the insects slurp up your blood. Now researchers find mosquito spit aggravates your immune system for days afterward. The findings could help scientists develop vaccines for mosquito-born diseases like Zika.

Rebecca Rico-Hesse, a virologist at Baylor College of Medicine in Houston, Texas, wanted to know how mosquitoes exploit our immune systems with their drool. So, she and her team exposed mice with human-like immune systems to live mosquitoes. Then, they sized up the mice’s immune response as it reacted to the mosquito spittle.

The bug’s saliva toyed with their immune systems in both bone marrow and skin cells with effects that lasted up to seven days after biting, the team reports today in PLoS: Neglected Tropical Diseases. The researchers say their discovery could explain how these tissues might act as virus incubators and help spread disease.

Master Manipulators

In 2012, Rico-Hesse was looking to untangle how Dengue virus causes Dengue hemorrhagic fever — an illness that affects 400 million people each year and can lead to death — when she came across a strange occurrence. Mice infected with the virus from mosquito bites fared far worse than mice that had received an injection of the virus but hadn’t been served as a mosquito meal. The result made Rico-Hesse take a step back.

It seems that mosquito bites caused the immune system to behave differently, and in ways that could potentially give infectious diseases a leg up.

To find out, Rico-Hesse and her team set starving Aedes aegypti mosquitoes on mice that had received a dose of human stem cells to make their immune systems look more like a human’s. Each mouse endured eight mosquito bites total. Then the team checked out different parts of the immune system — blood, bone marrow, spleen, and skin cells — six and 24 hours after biting, as well as seven days later. By then, the immune system should have returned to normal.

Sneaky Viruses

Instead, the team discovered immune cells that had disappeared from the skin at least six hours post-bite came back seven days later after maturing in bone marrow, something that shouldn’t have happened. If those cells harbored a virus, they could then pass it on to new mosquitoes, who could infect others.

The research is pointing out new ways in which mosquito bites affect our immune systems, and it goes beyond simple itching and scratching.

“Mosquito saliva has evolved to modify our immune system,” Rico-Hesse said. And as their new research shows, viruses and parasites could be hijacking that activity to get to the cells they reproduce in, like bone marrow cells, faster, according to her.

Essentially, viruses might be taking advantage of the immune system’s response to travel from their point of entry — the skin — to a place they can multiply in that’s away from attacks by the immune system.

“It’s mind-blowing,” Rico-Hesse said. “No one has ever seen this before.”

Ultimately, the work could lead to infection-blocking vaccines, said Duane Gubler, an international health expert who was not involved in the research.

That’s what Rico-Hesse hopes, too. “If we can make a vaccine that would protect us against the effects of the [mosquito] saliva, or blocking our immune reaction … then we could stop global vector-born diseases,” she said.

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Yet Another Study Says Vitamin Supplements Are Worthless

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Vitamin — the first four letters come from the Latin word for “life.” To sustain that, we need these organic compounds in small amounts, but it seems their purpose ends there.

New research reaffirms the counterintuitive notion that vitamin and mineral supplements aren’t the magical panacea we’ve been led to believe. It’s something that researchers have been finding for years, and a meta-analysis, summarizing the findings of 179 individual studies, published on Monday in the Journal of the American College of Cardiology found that most common vitamins provide precisely zero benefit to those taking them.

Non-vital Vitamins

Specifically, the study concluded that multivitamins, as well as calcium, and vitamins C and D are essentially powerless. They do no harm, but they might as well be placebos. These findings run contrary to popular wisdom, which instructs us to load up on supplements to reduce the risk of heart disease, cancer and premature death.

This isn’t the first time science has refuted vitamin worship. In 2013 a series of studies in the Annals of Internal Medicine, collectively including hundreds of thousands of participants, concurred that vitamins do not lead to any boost in health. In fact, the studies found that beta-carotene, vitamin E and possibly high doses of vitamin A actually slightly increase mortality.

The only supplement that may live up to its reputation, according to the new study, is folic acid. This, with or without vitamin B, may prevent cardiovascular disease and stroke.

The tradition of using vitamins and minerals for nutrient deficiencies dates back to 1747, when the British naval surgeon James Lind treated scurvy with citrus fruit, rich in vitamin C. Physicians routinely make such prescriptions, though usually only in cases where the patient has a demonstrated deficiency of a particular vitamin or nutrient.

Supplement Crazy

In recent years, though, we’ve come to view supplements as the gateway to general health and longevity. A Gallup poll in 2013 showed that 50 percent of Americans regularly take vitamins or multivitamins.

On the flip side, a comparison of Gallup polls in 1975 and 2016 reveals plunging public trust in the mainstream American medical system. This phenomenon may have contributed to the ascent of “natural” vitamin and mineral supplements.

But it probably also stems from rampant marketing and advertising. Thanks to the Dietary Supplement Health and Education Act of 1994, manufacturers don’t have to prove the to the Food and Drug Administration that their supplements work. They can claim their products work, though, as long as they keep it vague (“strengthens the body”) and don’t profess to truly treat anything.

Call it a healthcare failure, call it a marketing miracle. Either way, call a doctor before you pop another vitamin. Odds are they’ll tell you to stick to fruits and veggies.

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KNOW THE CAUSE: Lyme Disease and Fungus

Lyme Disease and Fungus

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Host:
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Guests:
Ross Pelton, RPH, PHD, CCN
Dr. Greg Emerson
Lindsey Crouch

Topics:
Dr Emerson Discusses Obesity
Probiotics That Produce Glutathione
The Vitamin You Don’t Need To Swallow
Lyme Disease and Fungus
Only Buy These If Organically Produced

Supplements:
Dr Ohirra’s Probiotics
Regactiv

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EFI – Dr Ohirra’s Probiotics
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877-673-2536

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Morgellons and Dope (Crack)

Even though this person in this video blog needs help with her drug addiction she shares her true story of being infected with morgellons. Everyone has their own way in dealing with this horrible disease. If you google Morgellons or resistant scabies mites you will come across forums of people questioning if some narcotic drugs could possibly get rid of these things. It’s not uncommon to hear individuals who gets high and complains about feeling bugs crawling all over them, biting them, etc. In reality in many cases it is true. Because of these narcotic drugs poisoning the system it drives them out of the body. Just as the same as if taking anti-parasitic drugs such as ivermectin.

Morgellons disease is a poorly understood condition characterized by small fibers, particles and bugs emerging from the skin. People with this condition often report feeling as if something is crawling on or stinging/ biting their skin.

In no way do we endorse or suggest in using any illegal substance to deal or attempt to get rid of morgellons or resistant scabies mites.

 

 

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